Skip Navigation LinksHome > Treatments

Treatments for Depression

Depression can present as single episode or recurrent episodes throughout a person’s lifetime. Fortunately, the majority of MDD episodes are mild-moderate in severity, and are successfully treated with talking therapy (psychotherapy) and/or medications. These are the usual treatments offered by most doctors and therapists treating depression. Unfortunately, there is a significant subset (estimated to be 5-20%) of MDD sufferers who do NOT respond to an array of antidepressant treatments, these individuals have a more severe form of depression referred to as treatment-resistant depression. Often, these individuals will require more advanced treatment options including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), or even deep brain stimulation (DBS). We at Washington University are committed to understanding this debilitating disorder and have established a clinic to carefully assess and direct treatments for those suffering from TRD.